Structure of PDB 7to3 Chain D

Receptor sequence
>7to3D (length=357) Species: 550 (Enterobacter cloacae) [Search protein sequence]
ELQPQFNEFLANIRPTDTQKEDWKSGARTLRERLKNFEPLKEIVVSTFLQ
GSIRRSTAIRPLGDKRPDVDIVVVTNLDHTRMSPTDAMDLFIPFLEKYYP
GKWETQGRSFGITLSYVELDLVITAIPESGAEKSHLEQLYKSESVLTVNS
LEEQTDWRLNKSWTPNTGWLSSAQVEDAPASEWKAHPLVLPDREKNEWGR
THPLAQIRWTAEKNRLCNGHYINLVRAVKWWRQQNSEDLPKYPKGYPLEH
LIGNALDNGTTSMAQGLVQLMDTFLSRWAAIYNQKSKPWLSDHGVAEHDV
MARLTAEDFCSFYEGIASAAEIARNALASEEPQESAQLWRQLFGSKFPLP
QKTGRFA
3D structure
PDB7to3 An E1-E2 fusion protein primes antiviral immune signalling in bacteria.
ChainD
Resolution2.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG D D69 D71 D68 D70
BS02 ATP D S53 R56 Q210 Y250 S52 R55 Q206 Y246
BS03 ADP D Q51 R109 L194 R197 R204 T205 R307 Q50 R108 L190 R193 R200 T201 R303
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7to3, PDBe:7to3, PDBj:7to3
PDBsum7to3
PubMed36755092
UniProtP0DSP4|CDND2_ENTH5 Cyclic AMP-AMP-GMP synthase (Gene Name=cdnD02)

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