Structure of PDB 7t5f Chain D

Receptor sequence
>7t5fD (length=420) Species: 1491 (Clostridium botulinum) [Search protein sequence]
PVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYT
FGYKPEDFNKSNRDVCEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLG
EKLLEMIINGIPYLGDRRVPLEEFNTNIASVTVNKLISNPGEVERKKGIF
ANLIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNN
VQENKGASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPNEKK
FFMQSTDAIQAEELYTFGGQDPSIITPSTDKSIYDKVLQNFRGIVDRLNK
VLVCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYKSLMFG
FTETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDM
EKEYRGQNKAINKQAYEEIS
3D structure
PDB7t5f Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.69: bontoxilysin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D H230 H234 E268 H225 H229 E263
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7t5f, PDBe:7t5f, PDBj:7t5f
PDBsum7t5f
PubMed34990480
UniProtP10844|BXB_CLOBO Botulinum neurotoxin type B (Gene Name=botB)

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