Structure of PDB 7svg Chain D

Receptor sequence
>7svgD (length=315) Species: 1596 (Lactobacillus gasseri) [Search protein sequence]
CTGLRFTDDQGNLYFGRNLDVGQDYGEGVIITPRNYPLPYKFLDNTTTKK
AVIGMGIVVDGYPSYFDCFNEDGLGIAGLNFPHFAKFSDGPIDGKINLAS
YEIMLWVTQNFTKVSDVKEALKNVNLVNEAINSSFAVAPLHWIISDKDEA
IIVEVSKQYGMKVFDDKLGVLTNSPDFNWHLTNLGNYTGLDPHDATAQSW
NGQKVAPWGVGTGSLGLPGDSIPADRFVKAAYLNVNYPTVKGEKANVAKF
FNILKSVAMIKGSVVNKLGSDEYTVYTACYSAATKTYYCNFENDFELKTY
KLDDETMNADKLITY
3D structure
PDB7svg Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut.
ChainD
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.-
3.5.1.24: choloylglycine hydrolase.
3.5.1.74: chenodeoxycholoyltaurine hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JN3 D V22 Y26 F67 N81 A137 L141 V21 Y25 F66 N80 A136 L140
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
Biological Process
GO:0006629 lipid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7svg, PDBe:7svg, PDBj:7svg
PDBsum7svg
PubMed36914755
UniProtA0A805Z5R7|CBH_LACGA Conjugated bile acid hydrolase (Gene Name=bsh)

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