Structure of PDB 7ssi Chain D

Receptor sequence
>7ssiD (length=213) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
KERERLEEKLEDANERIAELVKLEERQRIARDLEDTLGQKLSLIGLKSDL
ARKLIYKDPEQAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDELINIK
QILEAADIMFIYEEEKWPENISLLNENILSMCLKEAVTNVVKHSQAKTCR
VDIQQLWKEVVITVSDDGTFKGEENSFSHGLLGMRERLEFANGSLHIDTE
NGTKLTMAIPNNS
3D structure
PDB7ssi An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis.
ChainD
Resolution3.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ACP D E289 N293 K296 H297 S298 F324 K325 G326 S330 H335 G336 E135 N139 K142 H143 S144 F170 K171 G172 S176 H179 G180
BS02 MG D E289 N293 E135 N139
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0046983 protein dimerization activity
Biological Process
GO:0000160 phosphorelay signal transduction system
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7ssi, PDBe:7ssi, PDBj:7ssi
PDBsum7ssi
PubMed36693130
UniProtO34757|DESK_BACSU Sensor histidine kinase DesK (Gene Name=desK)

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