Structure of PDB 7rsh Chain D

Receptor sequence
>7rshD (length=401) Species: 154 (Spirochaeta thermophila) [Search protein sequence]
TYTLVWKVWILAVTLYFAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDLAFEPTLLAPSRLPDLLAALPLDLLVFALHLPSPLSLLSLVRLLKLIS
VQRSATRILSYRINPALLRLLSLVGFILLAAHGIACGWMSLQPPSENPAG
TRYLSAFYWTITTLTTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIGN
IASLVSKLDAAKLLHRERVERVTAFLSYKRISPELQRRIIEYFDYLWETR
RGYEEREVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHL
EPVIYGPGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRYAILSEGQFFG
EMALILRAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAAQIQELAVR
R
3D structure
PDB7rsh Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
ChainD
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP D F366 G367 E368 R377 F349 G350 E351 R360
BS02 PGW D G167 Y170 G150 Y153
BS03 PGW D A166 Y170 A149 Y153
BS04 PGW D L134 L138 V141 L117 L121 V124
BS05 PGW D F143 G150 F126 G133
BS06 PGW D L112 I116 L95 I99
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0044877 protein-containing complex binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:7rsh, PDBe:7rsh, PDBj:7rsh
PDBsum7rsh
PubMed36376326
UniProtG0GA88

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