Structure of PDB 7rs3 Chain D

Receptor sequence
>7rs3D (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR
ELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKL
LFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII
LLNSGVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQL
LLILSHIRHMSNKGMEHLYSMKNVVPSYDLLLEMLDA
3D structure
PDB7rs3 Dual-mechanism estrogen receptor inhibitors.
ChainD
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7OR D M343 L346 T347 A350 E353 L387 L391 F404 M421 I424 G521 L525 V533 V534 P535 M41 L44 T45 A48 E51 L85 L89 F102 M119 I122 G214 L218 V224 V225 P226
External links
PDB RCSB:7rs3, PDBe:7rs3, PDBj:7rs3
PDBsum7rs3
PubMed34452998
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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