Structure of PDB 7rje Chain D

Receptor sequence
>7rjeD (length=243) Species: 237561 (Candida albicans SC5314) [Search protein sequence]
TAAEHGLHPPAYNWPHNGMFETFDHASIRRGFQVYREVCAACHSLDRIAW
RNLVGVSHTTSEAKAMAEELEYDDEPDDEGKPRKRPGKLADYIPGPYENE
QAARAANQGAYPPDLSLIVKARHGGSDYIFSLLTGYPDEPPAGVVLPEGS
NYNPYFPGGAIAMGRVLFDDLVEYEDGTPATTSQMAKDVSTFLNWASEPE
HDDRKKWGLKALVVLSSLYLLSIWVKRFKWTPIKNRKFRFDPP
3D structure
PDB7rje Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
ChainD
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.8: quinol--cytochrome-c reductase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEC D V81 C82 C85 H86 N150 A153 P155 R165 Y171 L176 F199 M206 V209 V38 C39 C42 H43 N107 A110 P112 R122 Y128 L133 F156 M163 V166
Gene Ontology
Molecular Function
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0045333 cellular respiration
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0045275 respiratory chain complex III

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7rje, PDBe:7rje, PDBj:7rje
PDBsum7rje
PubMed34525326
UniProtA0A1D8PHA3|CYT1_CANAL Cytochrome b-c1 complex catalytic subunit, mitochondrial (Gene Name=CYT1)

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