Structure of PDB 7ri3 Chain D

Receptor sequence
>7ri3D (length=578) Species: 1940 (Streptomyces albireticuli) [Search protein sequence]
ENIQVAEITPSTRIVYRGVSPAEFIYLEGNKFSRAQSPTQGNDDPQWKAL
YTGSDANVSSRNITDNPGGVVKIEYPSDWKVLEITSTTPSQKWHNDMGEA
WPVWRAVKKWAASNQVDLPDVTASNIDDYLLLDELGKKKIILKKPIGEDD
VSSHEFIIPWKMAETVAQNKIDSTSDPAAKFFTPDDLDSTTKQPKDQAAV
RRILKKWDAYSCKGTFGVASLCGINVAAYKADIEKLIKDVYEDPNFSDLK
NRTGGPQKDKDTLKGYYERLKPKVETLRPLKAGVSSAVGAAGAISWAIGV
ADAFTSENVSSFDKAAAVTAIVPGLGECVGIANAIDKRDPEGLIINTISM
AALMASAAVPVLAPIGVALDAGLAAAQGVATVLEYLEIGQPARTPLPVSS
PKTHKGVTAAWVGSERIIAHRPRPGMRQHIFSVSIDSSKPEYTAPLIEVA
GVRADGKLDPSPEWIRIRQNHYPIPFRFEKLSGDSPYAFRCVLLRPTTIT
RTEPVYVTFAYMTSDMTCRTGESDPNKACSPNNPAIAVRFGSLVKNEDER
SVLAVTWPGPSIRPETNWIKLPYSIHPY
3D structure
PDB7ri3 Structures of distant diphtheria toxin homologs reveal functional determinants of an evolutionarily conserved toxin scaffold.
ChainD
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA D I233 E393 Y481 I224 E384 Y472
Gene Ontology
Molecular Function
GO:0047286 NAD+-diphthamide ADP-ribosyltransferase activity
GO:0090729 toxin activity
Cellular Component
GO:0005615 extracellular space

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:7ri3, PDBe:7ri3, PDBj:7ri3
PDBsum7ri3
PubMed35440624
UniProtA0A2A2D7J4

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