Structure of PDB 7r3b Chain D

Receptor sequence
>7r3bD (length=369) Species: 1590 (Lactiplantibacillus plantarum) [Search protein sequence]
RHLFTSESVSEGHPDKIADQISDAILDAMLAQDPQARVAVETSVTTGLVL
VFGEVSTKAYVDIQKVVRDTIKSIGYVDGQYGFDGDNCAVLVSLDEQSIG
AGDQGMMFGYAINETPELMPLPIALSHRLMRKIAALRKDGTIKWLRPDAK
AQVTVEYDEDNQPKRIDTVVLSTQHDPDVDLDTIRQTVIDQVIKAVLPAD
LLDDQTKYLVNPTGRFVIGGPQGDAGLTGRKVIVDTYGGFAHHGGGAFSG
KDATKVDRSASYAARYIAKNVVAAGLADQVEVQLAYAIGVAEPVSIAVDT
AGTGKVSDEALINAIRENFDLRPAGIIKMLDLQRPIYRQTAAYGHFGRTD
IDLPWEHTDKVDALKAAFK
3D structure
PDB7r3b Evolution of homo-oligomerization of methionine S-adenosyltransferases is replete with structure-function constrains.
ChainD
Resolution2.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.6: methionine adenosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP D H16 P17 D18 D174 K176 D250 R256 K257 H13 P14 D15 D148 K150 D224 R230 K231
BS02 MG D D18 R256 D15 R230
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004478 methionine adenosyltransferase activity
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006556 S-adenosylmethionine biosynthetic process
GO:0006730 one-carbon metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7r3b, PDBe:7r3b, PDBj:7r3b
PDBsum7r3b
PubMed35762725
UniProtQ88XB8|METK_LACPL S-adenosylmethionine synthase (Gene Name=metK)

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