Structure of PDB 7qrf Chain D

Receptor sequence
>7qrfD (length=80) Species: 11088 (Tick-borne encephalitis virus (WESTERN SUBTYPE)) [Search protein sequence]
ATVRKERDGSTVIRAEGKDAATQVRVENGTCVILATDMGSWCDDSLSYEC
VTIDQGEEPVDVDCFCRNVDGVYLEYGRCG
3D structure
PDB7qrf Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery.
ChainD
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D A1 V3 V24 R25 A1 V3 V24 R25
External links
PDB RCSB:7qrf, PDBe:7qrf, PDBj:7qrf
PDBsum7qrf
PubMed35764616
UniProtP14336|POLG_TBEVW Genome polyprotein

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