Structure of PDB 7qoz Chain D

Receptor sequence
>7qozD (length=322) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]
MVNVAVIGAAGGIGQSLSLLLLRELPFGSTLSLYDVVGAPGVAADLSHID
RAGITVKHAAGKLPPVPRDPALTELAEGVDVFVIVAGVPRKPGMTRDDLF
NVNAGIVMDLVLTCASVSPNACFCIVTNPVNSTTPIAAQTLRKIGVYNKN
KLLGVSLLDGLRATRFINNARHPLVVPYVPVVGGHSDVTIVPLYSQIPGP
LPDESTLKEIRKRVQVAGTEVVKAKAGRGSATLSMAEAGARFTMHVVKAL
MGLDTPMVYAYVDTDGEHECPFLAMPVVLGKNGIERRLPIGPITTVEKEM
LEEAVGVVKKNIAKGETFARSK
3D structure
PDB7qoz Crystal structure of NAD-bound glycosomal malate dehydrogenase from Trypanosoma cruzi
ChainD
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.37: malate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD D G11 G12 I13 Y34 D35 V36 A86 G87 P89 V126 N128 H185 M235 G11 G12 I13 Y34 D35 V36 A86 G87 P89 V126 N128 H185 M235
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0030060 L-malate dehydrogenase (NAD+) activity
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0019752 carboxylic acid metabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:7qoz, PDBe:7qoz, PDBj:7qoz
PDBsum7qoz
PubMed
UniProtA0A2V2XLH9

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