Structure of PDB 7qi1 Chain D

Receptor sequence
>7qi1D (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSMTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLS
VAYKNVVGARRSSWRVISSIEQKTNEKKQQMGKEYREKIEAELQDICNDV
LELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQ
AYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFD
EAIAELDTLNEESYKDSTLIMQLLRDNLTLWTS
3D structure
PDB7qi1 Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR.
ChainD
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D N40 R43 N44 V48 R58 R62 K122 R129 Y130 P167 I168 L174 N175 V178 E182 L222 N226 L229 N43 R46 N47 V51 R61 R65 K123 R130 Y131 P168 I169 L175 N176 V179 E183 L223 N227 L230
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