Structure of PDB 7qhh Chain D

Receptor sequence
>7qhhD (length=404) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL
TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFS
KPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFL
VSRFSPYEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLII
ISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRS
KIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYI
EQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKL
KNKWWYDKGECGAKDKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFC
YKSR
3D structure
PDB7qhh Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor.
ChainD
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU D Y450 G653 S654 T655 Y58 G241 S242 T243
BS02 79N D Y523 M527 Y533 F584 Y131 M135 Y141 F172
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0038023 signaling receptor activity
Biological Process
GO:0006811 monoatomic ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qhh, PDBe:7qhh, PDBj:7qhh
PDBsum7qhh
PubMed35136046
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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