Structure of PDB 7qen Chain D

Receptor sequence
>7qenD (length=1050) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
FSLSEYLTKFQTTDRESYPRLQDPSRELNVIIDQLAVSPEQIDASPDSLE
ALIDLCHDFPHLTPKLQTQLSYLISSSLSNLSKDIKANLSSNVNFTEIGG
LIPQWKRHLEEYGYLIQVLLTFLQDELHKVSSQSTNLNRSAKNSKNDSAN
VELFKRDCNQMENLLESITKLLEINLSKIFQTTPEKDLFIGLFTRPLFVL
LEIEPVTKVSSLKMFIQRILAMCVKNHGQSSSIQSSLMTNLTYFLHLSVF
NAELLKLLNDEYNYPQLTEDILKEISTRVFNAKDTTGPKAISNFLIKLSE
LSPGIMLRQMNLVITLLNNSSITLRCSVVEACGNIVAELAQDPQTMEHYK
QQIAVLIELLEERFQDSNPYVRTKAIQGCSKICDLSSKFNKSKAKFTSLA
VRSLQDRSSLVRRNSVKLLSKLLLKHPFKAIHGSQLRLSEWEEYLKGSES
QLNKLKLMIVYYKDAISFIKEIHKSIELISNLLFSKNRNEVLESMDFLVL
ADAFDIELSEFGIKKMLHLVWMKGTNDEGTSISVHLIECYKQLFLTAPDS
CNMQEKAAHIAKNLINLSIGASIADLASLEQLLGMMYEQKLIDQHVINIL
WAIYNSASKAGFSKEQIHGSIIILGMLSLADNEIALKGLESLLNIGLGAV
GLKDLTLCRYSCLALERMVPKRSTIAINQELEDVAVKKLYAIIINYTKDN
EYYPMCEQALSALFTISSKPDILATDLIREKTMMTFGKPQSSRVVSLSQL
LFIVGQVAIKTLVYLEKCEAEFKKRKIEAETRNGKTNEDDFTDAIQFVKE
NELLFGEKSILGKFCPIVEEIVSNSSRFSDPMLQRTATLCLEKLMCLSSK
YCEKSLPLLITVMEKSPDPTIRSNAVLGLGDMAVCFNNLVDENTDYLYRR
LHDENLMVQRTCLMTVTFLILAGQVKVKGQLGEMAKCLDNPDQGISDMCR
LFFTELASKDNAIYNGFIDIFSNLSSDDLLGKESFKKIIKFLLTFIDKER
HQKQLNEKLVGRLRKCETQKQWDDIAFVLNNLPYKNEDVTALLEQGFKVV
3D structure
PDB7qen A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
ChainD
Resolution3.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna D R142 K292 Y373 K377 L413 G597 K1120 E1121 R139 K289 Y370 K374 L410 G529 K998 E999
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0042393 histone binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0000278 mitotic cell cycle
GO:0007076 mitotic chromosome condensation
GO:0007130 synaptonemal complex assembly
GO:0010032 meiotic chromosome condensation
GO:0030261 chromosome condensation
GO:0030466 silent mating-type cassette heterochromatin formation
GO:0043007 maintenance of rDNA
GO:0044804 nucleophagy
GO:0051301 cell division
GO:0051307 meiotic chromosome separation
GO:0070058 tRNA gene clustering
GO:0070550 rDNA chromatin condensation
GO:1903342 negative regulation of meiotic DNA double-strand break formation
Cellular Component
GO:0000779 condensed chromosome, centromeric region
GO:0000796 condensin complex
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7qen, PDBe:7qen, PDBj:7qen
PDBsum7qen
PubMed35653469
UniProtQ06156|CND1_YEAST Condensin complex subunit 1 (Gene Name=YCS4)

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