Structure of PDB 7qem Chain D

Receptor sequence
>7qemD (length=426) Species: 83333,208964 [Search protein sequence]
MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMD
TVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESAIVRDPVTV
TPSTKIIELLQMAREYGFSGFPVVEQGELVGIVTGRDLRVKPNAGDTVAA
IMTPKDKLVTAREGTPLEEMKAKLYENRIEKMLVVDENFYLRGLVTFRDI
EKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAAGVDVLLIDSSH
GHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIGP
CTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAG
ASAVMVGSMLAGTEESPGEIELYQGRSYKSYVAYKGRLKEIIHQQMGGLR
SCMGLTGCGTIDELRTKAEFVRISGA
3D structure
PDB7qem Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases.
ChainD
Resolution3.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP D D337 G338 G360 S361 D334 G335 G357 S358
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7qem, PDBe:7qem, PDBj:7qem
PDBsum7qem
PubMed37338125
UniProtP0ADG7;
Q9HXM5

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