Structure of PDB 7q4q Chain D

Receptor sequence

>7q4qD (length=219) Species: 10090 (Mus musculus) [Search protein sequence]

QVQLVQSGAEVKKPGSSVKVSCKASGYTFSGYWMNWVRQAPGQGLEWIGQ
IYPGDGDTNYNGKFKGRVTITADKSTSTAYMELSSLRSEDTAVYYCARSI
TTVVLDYWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDY
FPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYT
CNVDHKPSNTKVDKRVESK

3D structure

PDB

7q4q Structural basis of human LRG1 recognition by Magacizumab, a humanized monoclonal antibody with therapeutic potential.

Chain

Resolution

1.65 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	D	G31 W33 Q50 Y52 T101 V103	G31 W33 Q50 Y52 T101 V103

External links

PDB	RCSB:7q4q, PDBe:7q4q, PDBj:7q4q
PDBsum	7q4q
PubMed	35647920

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