Structure of PDB 7ptj Chain D

Receptor sequence
>7ptjD (length=509) Species: 382 (Sinorhizobium meliloti) [Search protein sequence]
GKPNILIIMVDQLNGKLFPDGPADFLHAPNLKALAKRSARFHNNYTSSPL
SAPARASFMAGQLPSRTRVYDNAAEYQSSIPTYAHHLRRAGYYTALSGKM
HLVGPDQLHGFEERLTTDIYPADFGWTPDYRKPGERIDWWYHNLGSVTGA
GVAEITNQMEYDDEVAFLANQKLYQLSRENDDESRRPWCLTVSFTHPHDP
YVARRKFWDLYEDCEHLTPEVGAIPLDEQDPHSQRIMLSCDYQNFDVTEE
NVRRSRRAYFANISYLDEKVGELIDTLTRTRMLDDTLILFCSDHGDMLGE
RGLWFKMNFFEGSARVPLMIAGPGIAPGLHLTPTSNLDVTPTLADLAGIS
LEEVRPWTDGVSLVPMVNGVERTEPVLMEYAAEASYAPLVAIREGKWKYV
YCALDPEQLFDLEADPLELTNLAENPRGPVDQATLTAFRDMRAAHWDMEA
FDAAVRESQARRWVVYEALRNGAYYPWDHQPLQKASERYMRNHMNLDTLE
ESKRYPRGE
3D structure
PDB7ptj Structural insights into choline-O-sulfatase reveal the molecular determinants for ligand binding.
ChainD
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.6.6: choline-sulfatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 D H30 A31 P32 K35 H27 A28 P29 K32
BS02 CA D D14 S54 D296 H297 D11 S51 D293 H294
Gene Ontology
Molecular Function
GO:0008484 sulfuric ester hydrolase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0047753 choline-sulfatase activity
Biological Process
GO:0042425 choline biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ptj, PDBe:7ptj, PDBj:7ptj
PDBsum7ptj
PubMed35503214
UniProtO69787|BETC_RHIME Choline-sulfatase (Gene Name=betC)

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