Structure of PDB 7p7f Chain D

Receptor sequence
>7p7fD (length=285) Species: 9606 (Homo sapiens) [Search protein sequence]
RVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIES
KIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLK
TVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLA
KKYRHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLG
SLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLR
FDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK
3D structure
PDB7p7f Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes.
ChainD
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
2.7.11.26: [tau protein] kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADN D I15 S17 I23 A36 M82 L85 D132 L135 I148 I12 S14 I20 A33 M79 L82 D129 L132 I145
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7p7f, PDBe:7p7f, PDBj:7p7f
PDBsum7p7f
PubMed35353987
UniProtP48730|KC1D_HUMAN Casein kinase I isoform delta (Gene Name=CSNK1D)

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