Structure of PDB 7ohx Chain D

Receptor sequence
>7ohxD (length=424) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
EKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSG
KTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFH
SQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLK
ALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARI
SLRPGPLFINVLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSV
KYYAELLNYPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDI
PAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYL
KASKVPLNEYQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQI
DKLDLAKVAKSYGFPVPPKVNITI
3D structure
PDB7ohx Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
ChainD
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna D N153 R155 Q156 E159 Q441 R448 N112 R114 Q115 E118 Q376 R383
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008186 ATP-dependent activity, acting on RNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0042274 ribosomal small subunit biogenesis
GO:1990417 snoRNA release from pre-rRNA
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0030687 preribosome, large subunit precursor
GO:0032040 small-subunit processome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ohx, PDBe:7ohx, PDBj:7ohx
PDBsum7ohx
PubMed34813592
UniProtQ03532|HAS1_YEAST ATP-dependent RNA helicase HAS1 (Gene Name=HAS1)

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