Structure of PDB 7np4 Chain D

Receptor sequence
>7np4D (length=501) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
MQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRF
YWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLN
FRTGIVVEDNTDIILDPRRIKMKYLKSWFVVDFVSSIPVDYIFLIVETRI
DSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLAS
AVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSLNNMVNNSWGK
QYSYALFKAMSHMLCIGYGRQAPMGMSDVWLTMLSMIVGATCYAMFIGHA
TALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKM
FDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRF
EVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKETKLADGSYFGEICL
LTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDR
I
3D structure
PDB7np4 Gating movements and ion permeation in HCN4 pacemaker channels.
ChainD
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP D F659 G660 E661 I662 C663 R670 R711 R714 I715 F445 G446 E447 I448 C449 R456 R497 R500 I501
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006813 potassium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7np4, PDBe:7np4, PDBj:7np4
PDBsum7np4
PubMed34166608
UniProtQ9TV66|HCN4_RABIT Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Gene Name=HCN4)

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