Structure of PDB 7nk0 Chain D

Receptor sequence
>7nk0D (length=74) Species: 9606 (Homo sapiens) [Search protein sequence]
MLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLD
NWKRGDSPTEKHKKLYPSCRFVQS
3D structure
PDB7nk0 Structure-based identification of a new IAP-targeting compound that induces cancer cell death inducing NF-kappa B pathway.
ChainD
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C66 C69 H86 C93 C42 C45 H62 C69
External links
PDB RCSB:7nk0, PDBe:7nk0, PDBj:7nk0
PDBsum7nk0
PubMed34938412
UniProtQ13489|BIRC3_HUMAN Baculoviral IAP repeat-containing protein 3 (Gene Name=BIRC3)

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