Structure of PDB 7n86 Chain D

Receptor sequence
>7n86D (length=210) Species: 9606 (Homo sapiens) [Search protein sequence]
NVAPKFLANMTSVILPEDLPVGAQAFWLVAEDQDNDPLTYGMSGPNAYFF
AVTPKTGEVKLASALDYETLYTFKVTISVSDPYIQVQREMLVIVEDRNDN
APVFFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSE
HLFRILANGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLP
VFLSISVVDQ
3D structure
PDB7n86 Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.
ChainD
Resolution3.175 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D N1 V2 D32 D34 D36 D81 N1 V2 D32 D34 D36 D81
BS02 CA D E17 D66 E68 D99 E17 D66 E68 D99
BS03 CA D E17 E68 D96 R97 D99 D132 E17 E68 D96 R97 D99 D128
BS04 CA D N98 N100 D130 D132 A136 D188 N98 N100 D126 D128 A132 D184
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7n86, PDBe:7n86, PDBj:7n86
PDBsum7n86
PubMed34871294
UniProtQ9BYE9|CDHR2_HUMAN Cadherin-related family member 2 (Gene Name=CDHR2)

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