Structure of PDB 7mql Chain D

Receptor sequence
>7mqlD (length=261) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
IPHTHAHLVDAFQALGIRAGQALMLHASVKAVGAVMGGPNVILQALMDAL
TPDGTLMMYAGWQDIPDFIDSLPDALKAVYLEQHPPFDPATARAVRENSV
LAEFLRTWPCVHRSANPEASMVAVGRQAALLTANHALDYGYGVESPLAKL
VAIEGYVLMLGAPLDTITLLHHAEYLAKMRHKNVVRYPCPILRDGRKVWV
TVEDYDTGDPHDDYSFEQIARDYVAQGGGTRGKVGDADAYLFAAQDLTRF
AVQWLESRFGD
3D structure
PDB7mql Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa.
ChainD
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.81: aminoglycoside N(3)-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA D H31 A32 S33 V34 K35 P44 E102 N103 S104 V105 F109 P168 T171 H26 A27 S28 V29 K30 P39 E97 N98 S99 V100 F104 P163 T166
BS02 RIO D Y64 E123 D170 H176 T212 Y59 E118 D165 H171 T207
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046353 aminoglycoside 3-N-acetyltransferase activity
GO:0120225 coenzyme A binding
Biological Process
GO:0016999 antibiotic metabolic process
GO:0046356 acetyl-CoA catabolic process
GO:0046677 response to antibiotic
GO:0071236 cellular response to antibiotic
GO:1901742 2-deoxystreptamine metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7mql, PDBe:7mql, PDBj:7mql
PDBsum7mql
PubMed35921328
UniProtP29808|AACC3_PSEAI Aminoglycoside N(3)-acetyltransferase III (Gene Name=aacC3)

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