Structure of PDB 7m0n Chain D

Receptor sequence
>7m0nD (length=183) Species: 657776 (Influenza A virus (A/ruddy turnstone/New Jersey/Sg-00524/2008(H4N6))) [Search protein sequence]
MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD
GGSKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIE
IGVTRREVHTYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRA
RIKTRLFTIRQEMASRGLWDSFRQSERAAAELA
3D structure
PDB7m0n Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
ChainD
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RLT D Y24 H41 F105 L106 Y130 E133 K134 Y24 H41 F86 L87 Y111 E114 K115
BS02 MN D E80 D108 E61 D89
BS03 MN D H41 D108 E119 I120 H41 D89 E100 I101
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Biological Process
External links
PDB RCSB:7m0n, PDBe:7m0n, PDBj:7m0n
PDBsum7m0n
PubMed36603507
UniProtC6Y633

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