Structure of PDB 7l2u Chain D

Receptor sequence
>7l2uD (length=532) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKPGFY
FGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVAD
NTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKI
GVLAYILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVL
EVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMI
IFTAAAYYRPVEGLPPYKLKNTVGDYFRVTGEILSVSGGVYFFFRGIQYF
LQRRPSLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVASMVFSLA
MGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVV
TLIEDGKYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVIL
TYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
FRSGKLLQVGFTPDGKDDYRWCFRVDEVNWTT
3D structure
PDB7l2u Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
ChainD
Resolution3.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XKP D C634 F638 C415 F419
BS02 XJ7 D V508 D509 S510 Y511 S512 T550 R557 E570 L574 L699 Q700 V312 D313 S314 Y315 S316 T354 R361 E374 L378 L480 Q481
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7l2u, PDBe:7l2u, PDBj:7l2u
PDBsum7l2u
PubMed34496225
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

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