Structure of PDB 7l2t Chain D

Receptor sequence
>7l2tD (length=584) Species: 10116 (Rattus norvegicus) [Search protein sequence]
DSEFKDPETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASY
TDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPG
FYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEV
ADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSG
KIGVLAYILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNS
VLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLY
MIIFTAAAYYRPVEGLPPYKLKNTVGDYFRVTGEILSVSGGVYFFFRGIQ
YFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVASMVFS
LAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTA
VVTLIEDGKYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYV
ILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMR
KAFRSGKLLQVGFTPDGKDDYRWCFRVDEVNWTT
3D structure
PDB7l2t Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
ChainD
Resolution3.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 65I D L630 F638 L463 F471
BS02 XJ7 D D509 Y511 S512 R557 E570 Q700 D365 Y367 S368 R413 E426 Q533
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7l2t, PDBe:7l2t, PDBj:7l2t
PDBsum7l2t
PubMed34496225
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

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