Structure of PDB 7kh4 Chain D

Receptor sequence
>7kh4D (length=304) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819) [Search protein sequence]
HHHHGSMDKNIIIGAMTALITPFKNGKVDEQSYARLIKRQIENGIDAVVP
VGTTGESATLTWEEHRTCIEIAVETCKGTKVKVLAGAGSNATHEAVGLAK
FAKEHGADGILSVAPYYNKPTQQGLYEHYKAIAQSVDIPVLLYNVPGRTG
CEISTDTIIKLFRDCENIYGVKEASGNIDKCVDLLAHEPRMMLISGEDAI
NYPILSNGGKGVISVTSNLLPDMISALTHFALDENYKEAKKINDELYNIN
KILFCESNPIPIKTAMYLAGLIESLEFRLPLCSPSKENFAKIEEVMKKYK
IKGF
3D structure
PDB7kh4 Fluorescence-based Assay Development for Screening Novel Inhibitors of Dihydrodipicolinate Synthase from Campylobacter jejuni
ChainD
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.3.3.7: 4-hydroxy-tetrahydrodipicolinate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3VN D A52 L54 W56 H59 N84 E88 Y110 A58 L60 W62 H65 N90 E94 Y116
Gene Ontology
Molecular Function
GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
GO:0016829 lyase activity
Biological Process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0019877 diaminopimelate biosynthetic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7kh4, PDBe:7kh4, PDBj:7kh4
PDBsum7kh4
PubMed
UniProtQ9PPB4|DAPA_CAMJE 4-hydroxy-tetrahydrodipicolinate synthase (Gene Name=dapA)

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