Structure of PDB 7k9y Chain D

Receptor sequence

>7k9yD (length=418) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]

ALLERILARDNLITALKRVEANQGAPGIDGVSTDQLRDYIRAHWSTIHAQ
LLAGTYRPAPVRRVEIPKPGGGTRQLGIPTVVDRLIQQAILQELTPIFDP
DFSSSSFGFRPGRNAHDAVRQAQGYIQEGYRYVVDMDLEKFFDRVNHDIL
MSRVARKVKDKRVLKLIRAYLQAGVMIEGVKVQTEEGTPQGGPLSPLLAN
ILLDDLDKELEKRGLKFCRYADDCNIYVKSLRAGQRVKQSIQRFLEKTLK
LKVNEEKSAVDRPWKRAFLGFSFTPERKARIRLAPRSIQRLKQRIRQLTN
PNWSISMPERIHRVNQYVMGWIGYFRLVETPSVLQTIEGWIRRRLRLCQW
LQWKRVRTRIRELRALGLKETAVMEIANTRKGAWRTTKTPQLHQALGKTY
WTAQGLKSLTQRYFELRQ

3D structure

PDB

7k9y Structural basis for template switching by a group II intron-encoded non-LTR-retroelement reverse transcriptase.

Chain

Resolution

3.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	D	Y221 L270 Y318 G321 Y325	Y220 L269 Y317 G320 Y324
BS02	rna	D	R19 F110 R111 P112 G113 N115 P197	R18 F109 R110 P111 G112 N114 P196
BS03	rna	D	N23 G25 A26 I67 L77 I79 G192 G193 P197	N22 G24 A25 I66 L76 I78 G191 G192 P196
BS04	DTP	D	K69 R75 L77 D138 L139 E140 K141 F142 F143 D223 K258	K68 R74 L76 D137 L138 E139 K140 F141 F142 D222 K257
BS05	MG	D	D138 L139 D223	D137 L138 D222

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003964	RNA-directed DNA polymerase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006278	RNA-templated DNA biosynthetic process
GO:0006974	DNA damage response
GO:0051607	defense response to virus

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:7k9y, PDBe:7k9y, PDBj:7k9y
PDBsum	7k9y
PubMed	34280434
UniProt	E2GM63

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