Structure of PDB 7jk3 Chain D

Receptor sequence
>7jk3D (length=441) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
PEADRELVSIRRFLKERLQRDYTTLRGYAKERSNVRLLLQRTAEMGESNS
LLLLGPRGSGKTTLINSVLADLLPNKSFGENTLIVHLDGNLHTDDRVALK
SITVQMQLENAADGKVFGSFAENLAFLLQCLKAGGKHSKSVIFILEEFDL
FCAHHNQTLLYNLFDVSQSAQAPICVLGVTCRLDVIELLEKRVKSRFSHR
QVFLFPSLRRFEDYVDLCRDLLSLPTGNSLLLAAEKIYNLQNIYFSRNHF
DPGEYGFSPRLRDAWNKQICKVLATQQARSTLQALHDFDISEAYLKNFLF
RLVAHLRPQSPHITAEKMAAVGSQFEGDDKIELLCGLSVLELCLIIAIKH
HSQIYDRDSFNFEIIYARFSKFAKVSTTMQAVERSIVLKAFEHLRIAELI
MPLTVQKEFEMHKLALTYSQIHHCMQRYQALPTEVAQWAQS
3D structure
PDB7jk3 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
ChainD
Resolution3.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna D R97 S120 F121 R96 S119 F120
BS02 ATP D L26 R27 R58 S60 G61 K62 T63 T64 E298 K302 L25 R26 R57 S59 G60 K61 T62 T63 E292 K296
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0016887 ATP hydrolysis activity
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
Cellular Component
GO:0000808 origin recognition complex
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005664 nuclear origin of replication recognition complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7jk3, PDBe:7jk3, PDBj:7jk3
PDBsum7jk3
PubMed32848132
UniProtQ9W102

[Back to BioLiP]