Structure of PDB 7h9e Chain D

Receptor sequence
>7h9eD (length=159) Species: 37124 (Chikungunya virus) [Search protein sequence]
PSYRVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSATP
VGTAKTVMCGTYPVIHAVGPNFSNYTESEGDRELAAAYREVAKEVTRLGV
NSVAIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKEWEKK
ISEAIQMRT
3D structure
PDB7h9e Group deposition for crystallographic fragment screening of Chikungunya virus nsP3 macrodomain
ChainD
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 4FS D D10 V33 Y142 D9 V32 Y141
BS02 4FS D R8 M9 R144 R7 M8 R143
External links
PDB RCSB:7h9e, PDBe:7h9e, PDBj:7h9e
PDBsum7h9e
PubMed
UniProtQ8JUX6|POLN_CHIKS Polyprotein P1234

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