Structure of PDB 7f9u Chain D

Receptor sequence
>7f9uD (length=480) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFF
DDEIKKMGVENSYFPMFVSRHKLEKPEVAWVTHYGDSPLPEKIAIRPTSE
TIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGH
TAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTT
TVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGC
TTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFENTGEILGKCRELK
TMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARV
VRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFD
EVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEMTGAMKTLCI
PFDQPPMPEGTKCFYTGKPAKRWTLWGRSY
3D structure
PDB7f9u TgPRS with double inhibitors
ChainD
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.15: proline--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HFG D E418 V419 P438 T439 E441 R470 W487 H491 F534 H560 E77 V78 P97 T98 E100 R129 W146 H150 F193 H219
BS02 1TI D R470 E472 K474 P476 L480 R481 T482 F485 Q555 A557 T592 R594 R129 E131 K133 P135 L139 R140 T141 F144 Q214 A216 T251 R253
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f9u, PDBe:7f9u, PDBj:7f9u
PDBsum7f9u
PubMed
UniProtA0A7J6JUK2

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