Structure of PDB 7f97 Chain D

Receptor sequence
>7f97D (length=475) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAF
FNKEIKKLNVENSYFPLFVTKNKLEKEKNEVAWVTKYGDSNLPEEIAIRP
TSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQ
EGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGAN
FTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTS
WGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKNAIHSYCKDI
EKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCV
IVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSF
SEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLSGAMKPLCIPLDQP
PMPPNMKCFWSGKPAKRWCLFGRSY
3D structure
PDB7f97 Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with L-proline and compound L97
ChainD
Resolution2.394 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.1.1.15: proline--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PRO D T359 E361 W407 E409 F454 H480 S508 W509 G510 T101 E103 W149 E151 F196 H222 S250 W251 G252
BS02 1XK D R390 E392 K394 Q395 P396 R401 T402 F405 Q475 A477 G510 C511 T512 R514 R132 E134 K136 Q137 P138 R143 T144 F147 Q217 A219 G252 C253 T254 R256
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7f97, PDBe:7f97, PDBj:7f97
PDBsum7f97
PubMed
UniProtQ8I5R7|SYP_PLAF7 Proline--tRNA ligase (Gene Name=proRS)

[Back to BioLiP]