Structure of PDB 7eor Chain D

Receptor sequence
>7eorD (length=770) Species: 9606 (Homo sapiens) [Search protein sequence]
KIVNIGAVLSTRKHEQMFREAVNQANKRHWKIQLNATSVTHKPNAIQMAL
SVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMS
IYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGRAA
QKRLETLLEERESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASED
DAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGILGLQLINGKN
ESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLM
SSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPND
RKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTV
NGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEV
HLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQY
IEFSKPFKYQGLTILVKKEIPQPFQSTLWLLVGLSVHVVAVMLYLLDRFS
LTLSSAMWFSWGVLLSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRP
RITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVCLSTMYRHMEKHNYE
SAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGM
RKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQTFENMAGVFMLVAGGI
VAGIFLIFIEIAYKRHKDAR
3D structure
PDB7eor Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors.
ChainD
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 6RM D I519 P532 Y535 G757 I493 P506 Y509 G695
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:7eor, PDBe:7eor, PDBj:7eor
PDBsum7eor
PubMed34186027
UniProtQ05586|NMDZ1_HUMAN Glutamate receptor ionotropic, NMDA 1 (Gene Name=GRIN1)

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