Structure of PDB 7dhy Chain D

Receptor sequence
>7dhyD (length=194) Species: 9606 (Homo sapiens) [Search protein sequence]
SVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQL
WVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLI
RVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGS
MNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENL
3D structure
PDB7dhy Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.
ChainD
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ARS D C124 M133 C135 C141 C29 M38 C40 C46
BS02 ZN D C176 H179 C238 C242 C81 H84 C143 C147
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7dhy, PDBe:7dhy, PDBj:7dhy
PDBsum7dhy
PubMed33357454
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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