Structure of PDB 7d3f Chain D

Receptor sequence
>7d3fD (length=272) Species: 9606 (Homo sapiens) [Search protein sequence]
LGHTFPFYAGPKPTFPMDTTLASIIMIFLTALATFIVILPGIRGKTRLFW
LLRVVTSLFIGAAILAVNFSSEWSVGQVSTNTSYKAFSSEWISADIGLQV
GLGGVNITLTGTPVQQLNETINYNEEFTWRLGENYAEEYAKALEKGLPDP
VLYLAEKFTPRSPCGLYRQYRLAGHYTSAMLWVAFLCWLLANVMLSMPVL
VYGGYMLLATGIFQLLALLFFSMATSLTSPCPLHLGASVLHTHHGPAFWI
TLTTGLLCVLLGLAMAVAHRMQ
3D structure
PDB7d3f Structures of human dual oxidase 1 complex in low-calcium and high-calcium states.
ChainD
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN D Y126 N127 E128 K148 Y123 N124 E125 K145
BS02 MAN D T123 I124 N125 Y126 T120 I121 N122 Y123
BS03 MAN D E122 T123 Y126 E119 T120 Y123
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0008104 protein localization
GO:0010729 positive regulation of hydrogen peroxide biosynthetic process
GO:0015031 protein transport
GO:0042743 hydrogen peroxide metabolic process
GO:0045666 positive regulation of neuron differentiation
GO:0050727 regulation of inflammatory response
GO:2000379 positive regulation of reactive oxygen species metabolic process
GO:2000609 regulation of thyroid hormone generation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7d3f, PDBe:7d3f, PDBj:7d3f
PDBsum7d3f
PubMed33420071
UniProtQ1HG43|DOXA1_HUMAN Dual oxidase maturation factor 1 (Gene Name=DUOXA1)

[Back to BioLiP]