Structure of PDB 7csc Chain D

Receptor sequence
>7cscD (length=309) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
KTRVLVVGATGYIGKRIVRACLAEGHETYVLQRPEIGLEIEKVQLFLSFK
KLGARIVEGSFSDHQSLVSAVKLVDVVVSAMSGVHFRSHNILVQLKLVEA
IKEAGNVKRFLPSEFGMDPPRMGHALPPGRETFDQKMEVRQAIEAAGIPY
TYVVGACFAAYFAGNLSQMVTLLPPKEKVNIYGDGNVKVVFADEDDIAKY
TAKTLNDPRTLNKTVNIRPPDNVLTQLELVQIWEKLTGKELEKTNIAAQD
FLANIEQMEIPHQAGIGHFYHIFYEGCLTDHEVGEDEEASSLYPDVKYKR
MDDYLRMFL
3D structure
PDB7csc Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
ChainD
Resolution2.51512 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.23.1.1: (+)-pinoresinol reductase.
1.23.1.3: (-)-pinoresinol reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GEF D F94 M125 Y169 F170 M177 V178 H276 F277 F86 M117 Y161 F162 M169 V170 H268 F269
BS02 NDP D G16 T18 G19 Y20 I21 R41 K50 A88 M89 S90 V92 R95 N98 S121 F123 K144 C165 F166 G8 T10 G11 Y12 I13 R33 K42 A80 M81 S82 V84 R87 N90 S113 F115 K136 C157 F158
Gene Ontology
Molecular Function
GO:0010283 pinoresinol reductase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0009807 lignan biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7csc, PDBe:7csc, PDBj:7csc
PDBsum7csc
PubMed33990581
UniProtQ9FVQ6|PILR1_ARATH Pinoresinol reductase 1 (Gene Name=PRR1)

[Back to BioLiP]