Structure of PDB 7cq7 Chain D

Receptor sequence
>7cq7D (length=676) Species: 9606 (Homo sapiens) [Search protein sequence]
YESLDYDNSENQLFLEEERRINHRTVEIKRWVICALIGILTGLVACFIDI
VVENLAGLKYRVIKGNIDKFTEKGGLSFSLLLWATLNAAFVLVGSVIVAF
IEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGGLAVGK
EGPMIHSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAG
VSAAFGAPVGGVLFSLEEGASFWNQFLTWRIFFASMISTFTLNFVLSIYH
GNMWDLSSPGLINFGRFDSEKMAYTIHEIPVFIAMGVVGGVLGAVFNALN
YWLTMFRIRYIHRPCLQVIEAVLVAAVTATVAFVLIYSSRDCQPLQGGSM
SYPLQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPLTLGLFTLV
YFFLACWTYGLTVSAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGK
YALMGAAAQLGGIVRMTLSLTVIMMEATSNVTYGFPIMLVLMTAKIVGDV
FIEGLYDMHIQLQSVPFLHWEAPVTSHSLTAREVMSTPVTCLRRREKVGV
IVDVLSDTASNHNGFPVVARLQGLILRSQLIVLLKHKVFVELRLKDFRDA
YPRFPPIQSIHVSQDERECTMDLSEFMNPSPYTVPQEASLPRVFKLFRAL
GLRHLVVVDNRNQVVGLVTRKDLARY
3D structure
PDB7cq7 Structure of the human CLCN7-OSTM1 complex with ADP
ChainD
Resolution3.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP D E95 H658 N659 R767 T783 K785 D786 E2 H562 N563 R653 T669 K671 D672
Gene Ontology
Molecular Function
GO:0005247 voltage-gated chloride channel activity
GO:0005254 chloride channel activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015108 chloride transmembrane transporter activity
GO:0015297 antiporter activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006821 chloride transport
GO:0030321 transepithelial chloride transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0016020 membrane
GO:0034707 chloride channel complex
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cq7, PDBe:7cq7, PDBj:7cq7
PDBsum7cq7
PubMed
UniProtP51798|CLCN7_HUMAN H(+)/Cl(-) exchange transporter 7 (Gene Name=CLCN7)

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