Structure of PDB 7coi Chain D

Receptor sequence
>7coiD (length=208) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
DKFSAALAKNKEWAAKCSQEHPELLPTLAVGQHPEILWIGCSDSRCPETT
ILGLLPGDVFTHRNIANVIHPADLSSGAVIEFAVRHLRVKHVVICGHTKC
GGVAAALGNKGLGILDPWLIPLRQLREQHLAELQSLSRDEAVVRLAELNV
KEGLKALTQKSVVLEAMQERGLQVHGLIYDVGSGFLRQLDAAEPEEALKA
RLTSFKTD
3D structure
PDB7coi Crystal Structure of beta-Carbonic Anhydrase CafA from the Fungal Pathogen Aspergillus fumigatus .
ChainD
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ACT D C119 D121 H175 C178 G179 C41 D43 H97 C100 G101
BS02 ZN D C119 H175 C178 C41 H97 C100
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0015976 carbon utilization
GO:0034599 cellular response to oxidative stress
GO:0071244 cellular response to carbon dioxide
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Cellular Component
External links
PDB RCSB:7coi, PDBe:7coi, PDBj:7coi
PDBsum7coi
PubMed32975213
UniProtQ4WQ18

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