Structure of PDB 7cll Chain D

Receptor sequence
>7cllD (length=424) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
PIIEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVEL
RDGGDRYGGKGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPD
KSRLGGNAILGVSLAVAKAAADSAELPLFRYVGGPNAHILPVPMMNILNG
GAHADTAVDIQEFMVAPIGAPSFVEALRWGAEVYHALKSVLKKEGLSTGL
GDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALDAAATEFFTDG
TGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASI
GDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTL
AHHGGYRTMISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQ
LLRIEEALGDAARYAGDLAFPRFA
3D structure
PDB7cll Mycobacterium tubeculosis enolase in complex with 2-Phosphoglycerate
ChainD
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.11: phosphopyruvate hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG D D241 E283 D310 D240 E282 D309
BS02 2PG D G40 A41 S42 H154 Q162 E163 E204 D241 D310 K335 H363 R364 S365 K386 G39 A40 S41 H153 Q161 E162 E203 D240 D309 K334 H362 R363 S364 K385
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006096 glycolytic process
Cellular Component
GO:0000015 phosphopyruvate hydratase complex
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0009986 cell surface

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cll, PDBe:7cll, PDBj:7cll
PDBsum7cll
PubMed37860976
UniProtP9WNL1|ENO_MYCTU Enolase (Gene Name=eno)

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