Structure of PDB 7ckq Chain D

Receptor sequence
>7ckqD (length=1137) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
FEYMNIGLASPDKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFGPTK
DWECHCGKYKRVRYKGVVCDRCGVEVTRAKVRRERMGHIELAAPVSHIWY
FKGIPSRMGLVLDMSPRALEEVIYFASYVVTDPANTPLEKKQLLSEKEYR
AYLDKYGNKFQASMGAEAIHKLLQDIDLVKEVDMLKEELKTSQGQRRTRA
IKRLEVLEAFRNSGNKPSWMILDVLPVIPPELRPMVQLDGGRFATSDLND
LYRRVINRNNRLKRLLDLGAPSIIVQNEKRMLQEAVDALIDNGRRGRPVT
GPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPHLKMYQCG
LPKEMALELFKPFVMKELVEKGLAHNIKSAKRKIERVQPEVWDVLESVIK
EHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVCTAYNADFDGDQMA
VHVPLSAEAQAEARILMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLER
AGAVGEGMVFKNTDEALLAYQNGYVHLHTRVAVAANSLQRSKLLITTVGK
LVFNEILPESFPYMNEPTKSNIEEDVKAVIAQQPINAPFKKGILGKIIAE
IFKRFHITETSKMLDRMKNLGFKYSTKAGITVGVSDIVVLDDKQEILEEA
QSKVDNVMKQFRRGLITEEERYERVISIWSAAKDVIQGKLMKSLDELNPI
YMMSDSGARGNASNFTQLAGMRGLMANPAGRIIELPIKSSFREGLTVLEY
FISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIIRETDCGTDRGILA
KPLKEGTETIERLEERLIGRFARKQVKHPETGEVLVNENELIDEDKALEI
VEAGIEEVWIRSAFTCNTPHGVCKRCYGRNLATGSDVEVGEAVGIIAAQS
IGEPGTQLTGLPRIQELFEARNPATITEIDGTVVEINEVRDKQQEIVVQG
AVETRSYTAPYNSRLKVAEGDKITRGQVLTEGSIDPKELLKVTDLTTVQE
YLLHEVQKVYRMQGVEIGDKHVEVMVRQMLRKVRVGDTDVLPGTLLDIHQ
FTEANKKVLLEGNRPATGRPVLLGITKASLETDSFLSAASFQETTRVLTD
AAIKGKRDELLGLKENVIIGKLVPAGTGMMKYRKVKP
3D structure
PDB7ckq The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription.
ChainD
Resolution4.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D Y36 P111 P122 R303 K1125 Y30 P105 P116 R297 K1077
BS02 dna D K321 G322 Q1140 E1141 K315 G316 Q1092 E1093
BS03 MG D D449 D451 D443 D445
BS04 ZN D C75 C78 C69 C72
BS05 ZN D C899 C902 C873 C876
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0046677 response to antibiotic
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ckq, PDBe:7ckq, PDBj:7ckq
PDBsum7ckq
PubMed33293519
UniProtP37871|RPOC_BACSU DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC)

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