Structure of PDB 7ccr Chain D

Receptor sequence
>7ccrD (length=92) Species: 9606 (Homo sapiens) [Search protein sequence]
SRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTS
3D structure
PDB7ccr Structural basis for nucleosome-mediated inhibition of cGAS activity.
ChainD
Resolution4.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R33 Y42 S55 S56 R86 S87 T88 R2 Y11 S24 S25 R55 S56 T57
BS02 dna D K34 Y40 K3 Y9
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7ccr, PDBe:7ccr, PDBj:7ccr
PDBsum7ccr
PubMed33051594
UniProtP06899|H2B1J_HUMAN Histone H2B type 1-J (Gene Name=H2BC11)

[Back to BioLiP]