Structure of PDB 7ccq Chain D

Receptor sequence
>7ccqD (length=92) Species: 9606 (Homo sapiens) [Search protein sequence]
SRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTS
3D structure
PDB7ccq Structural basis for nucleosome-mediated inhibition of cGAS activity.
ChainD
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna D Y42 I54 S55 S56 R86 S87 T88 Y11 I23 S24 S25 R55 S56 T57
BS02 dna D I39 Y40 I8 Y9
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:7ccq, PDBe:7ccq, PDBj:7ccq
PDBsum7ccq
PubMed33051594
UniProtP06899|H2B1J_HUMAN Histone H2B type 1-J (Gene Name=H2BC11)

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