Structure of PDB 7c89 Chain D

Receptor sequence
>7c89D (length=244) Species: 272557 (Aeropyrum pernix K1) [Search protein sequence]
PGSIPLIGERFPEMEVTTDHGVIKLPDHYVSQGKWFVLFSHPADFTPVST
TEFVSFARRYEDFQRLGVDLIGLSVDSVCSHIKWKEWIERHIGVRIPFPI
IADPQGTVARRLGLLHAESATHTVRGVFIVDARGVIRTMLYYPMELGRLV
DEILRIVKALKLGDSLKRAVPADWPNNEIIGEGLIVPPPTTEDQARARME
SGQYRSLDWWFSWDTPASRDDVEEARRYLRRAAEKPAKLLYEEA
3D structure
PDB7c89 Rebuilding Ring-Type Assembly of Peroxiredoxin by Chemical Modification.
ChainD
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.11.1.24: thioredoxin-dependent peroxiredoxin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FL0 D A44 T47 H123 A43 T46 H122
BS02 FL0 D V79 C80 V78 C79
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0008379 thioredoxin peroxidase activity
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
GO:0042802 identical protein binding
GO:0051920 peroxiredoxin activity
GO:0140824 thioredoxin-dependent peroxiredoxin activity
Biological Process
GO:0006979 response to oxidative stress
GO:0033554 cellular response to stress
GO:0042744 hydrogen peroxide catabolic process
GO:0045454 cell redox homeostasis
GO:0070301 cellular response to hydrogen peroxide
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7c89, PDBe:7c89, PDBj:7c89
PDBsum7c89
PubMed33334100
UniProtQ9Y9L0|TDXH_AERPE Peroxiredoxin (Gene Name=APE_2278)

[Back to BioLiP]