Structure of PDB 7c18 Chain D

Receptor sequence
>7c18D (length=460) Species: 221988 ([Mannheimia] succiniciproducens MBEL55E) [Search protein sequence]
AFRIEKDTMGEVQVPADKYWAAQTERSRNNFKIGPAASMPHEIIEAFGYL
KKAAAFANTDLGVLPAEKRDLIGQACDEILARKLDDQFPLVIWQTGSGTQ
SNMNLNEVIANRAHVINGGKLGEKSIIHPNDDVNKSQSSNDTYPTAMHIA
AYKKVVEATIPAVERLQKTLAAKAAEFKDVVKIGRTHLMDATPLTLGQEF
SGYAAQLSFGLTAIKNTLPHLRQLALGGTAVGTGLNTPKGYDVKVAEYIA
KFTGLPFITAENKFEALATHDAIVETHGALKQVAMSLFKIANDIRLLASG
PRSGIGEILIPENEPGCSIMPGKVNPTQCEAMTMVAAQVLGNDTTISFAG
SQGHFELNVFKPVMAANFLQSAQLIADVCISFDEHCATGIQPNTPRIQHL
LDSSLMLVTALNTHIGYENAAKIAKTAHKNGTTLREEAINLGLVSAEDFD
KWVVPADMVG
3D structure
PDB7c18 Structural studies reveal the molecular mechanism of isocitrate lyase from Chloroflexus aurantiacus
ChainD
Resolution2.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.2: fumarate hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUM D T188 H189 T186 H187
BS02 FUM D T101 S140 S141 N142 T99 S138 S139 N140
BS03 FUM D C319 S320 M322 K325 N327 C317 S318 M320 K323 N325
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004333 fumarate hydratase activity
GO:0016829 lyase activity
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0006106 fumarate metabolic process
GO:0006108 malate metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7c18, PDBe:7c18, PDBj:7c18
PDBsum7c18
PubMed
UniProtQ65UJ3

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