Structure of PDB 7bya Chain D

Receptor sequence
>7byaD (length=311) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
AMKRKKISVIGAGFTGATTAFLLAQKELGDVVLVDIPQLENPTKGKALDM
LEASPVLGFDANIIGTSDYADTADSDIVVITAGIARKPGMSRDDLVTTNQ
KIMKQVTKEVVKYSPNCYIIVLTNPVDAMTYTVFKESGFPKNRVIGQSGV
LDTARFRTFVAEELNISVKDVTGFVLGGHGDDMVPLVRYSYAGGIPLEKL
IPKDRLDAIVERTRKGGGEIVNLLGNGSAYYAPAASLVEMVEAILKDQRR
ILPAIAYLEGEYGYEGIYLGVPTILGGNGIEKVIELELTEEEKAALAKSV
ESVKNVMRMLE
3D structure
PDB7bya Structural analysis and reaction mechanism of malate dehydrogenase from Geobacillus stearothermophilus.
ChainD
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.37: malate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 APR D G13 F14 T15 D35 I36 T81 A82 G83 I84 I102 Q105 T123 N124 G13 F14 T15 D35 I36 T81 A82 G83 I84 I102 Q105 T123 N124
BS02 OAA D R86 R92 N124 L151 R155 H179 G217 R86 R92 N124 L151 R155 H179 G217
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004459 L-lactate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0030060 L-malate dehydrogenase (NAD+) activity
Biological Process
GO:0006089 lactate metabolic process
GO:0006090 pyruvate metabolic process
GO:0006099 tricarboxylic acid cycle
GO:0019752 carboxylic acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7bya, PDBe:7bya, PDBj:7bya
PDBsum7bya
PubMed33723609
UniProtA0A143T1U9

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