Structure of PDB 7bjv Chain D

Receptor sequence
>7bjvD (length=240) Species: 7102 (Heliothis virescens) [Search protein sequence]
NVPPLTANQKSLIARLVYYQEGYEQPSEEDLKRVTQTWDSDMPFRQITEM
TILTVQLIVEFAKGLPGFSKISQSDQITLLKACSSEVMMLRVARRYDAAT
DSVLFANNQAYTRDNYRKAGMAYVIEDLLHFCRCMYSMMMDNVHYALLTA
IVIFSDRPGLEQPSLVEEIQRYYLNTLRVYILNQNSASPRSAVIFGKILG
ILTEIRTLGMQNSNMCISLKLKNRKLPPFLEEIWDVADVA
3D structure
PDB7bjv Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP.
ChainD
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U0H D T343 M380 Y403 Y408 V416 Q503 N504 W526 T51 M88 Y111 Y116 V124 Q211 N212 W234
BS02 MG D Y304 G356 Y19 G64
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0035100 ecdysone binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0035076 ecdysone receptor signaling pathway
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7bjv, PDBe:7bjv, PDBj:7bjv
PDBsum7bjv
PubMed33746550
UniProtO18473|ECR_HELVI Ecdysone receptor (Gene Name=EcR)

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