Structure of PDB 7bju Chain D

Receptor sequence
>7bjuD (length=231) Species: 7102 (Heliothis virescens) [Search protein sequence]
NVPPLTANQKSLIARLVYYQEGYEQPSEEDLKRVSDMPFRQITEMTILTV
QLIVEFAKGLPGFSKISQSDQITLLKACSSEVMMLRVARRYDAATDSVLF
ANNQAYTRDNYRKAGMAYVIEDLLHFCRCMYSMMMDNVHYALLTAIVIFS
DRPGLEQPSLVEEIQRYYLNTLRVYILNQNSASPRSAVIFGKILGILTEI
RTLGMQNSNMCISLKLKNRKLPPFLEEIWDV
3D structure
PDB7bju Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP.
ChainD
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 834 D T343 M381 V384 Y403 Y408 M413 V416 L420 Q503 N504 M507 W526 T46 M84 V87 Y106 Y111 M116 V119 L123 Q206 N207 M210 W229
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0035100 ecdysone binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0035076 ecdysone receptor signaling pathway
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7bju, PDBe:7bju, PDBj:7bju
PDBsum7bju
PubMed33746550
UniProtO18473|ECR_HELVI Ecdysone receptor (Gene Name=EcR)

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