Structure of PDB 7atu Chain D

Receptor sequence
>7atuD (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
IKVTHTGEVMVMKERFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYLNF
ITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDL
NSHNCLVRENKNVVVADFGLARLMGNPYWMAPEMINGYDEKVDVFSFGIV
LCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCD
LDPEKRPSFVKLEHWLETLRMHLGHLPLGPQLEQLDRGFWETY
3D structure
PDB7atu The LIMK1 Kinase Domain Bound To LIJTF500025
ChainD
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D460 N462 H464 N465 D478 N512
Catalytic site (residue number reindexed from 1) D99 N101 H103 N104 D117 N126
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RXN D K368 M388 V396 L397 F399 F411 T413 L451 H458 D478 F479 R483 K13 M31 V39 L40 F42 F50 T52 L90 H97 D117 F118 R122
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7atu, PDBe:7atu, PDBj:7atu
PDBsum7atu
PubMed
UniProtP53667|LIMK1_HUMAN LIM domain kinase 1 (Gene Name=LIMK1)

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