Structure of PDB 6zjc Chain D

Receptor sequence
>6zjcD (length=220) Species: 9796 (Equus caballus) [Search protein sequence]
VKPMLHYFNGRGRMEPIRWLLAAAGVEFEETFIDTPEDFEKLKNDGSLMF
QQVPMVEIDGMKLVQSRAILNYVAAKHNLYGKDIKERALIDMYIEGVADL
NEMILLLPITPPAEKDAKIMLIKDRTTNRYLPAFEKVLKSHGEDYLVGNR
LSRADIHLVELLYLVEELDPSLLTNFPLLKALKARISNLPTVKKFLQPGG
ARKPPGDEKSVEKSRKIFKF
3D structure
PDB6zjc Structural and functional analysis of the inhibition of equine glutathione transferase A3-3 by organotin endocrine disrupting pollutants.
ChainD
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH D Y9 R15 F41 Q54 V55 Q67 S68 Y7 R13 F39 Q52 V53 Q65 S66
BS02 QLT D Y9 F222 Y7 F220 MOAD: ic50=9.6uM
BS03 GSH D D101 R131 D99 R129
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:6zjc, PDBe:6zjc, PDBj:6zjc
PDBsum6zjc
PubMed33162212
UniProtM9ZT87

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