Structure of PDB 6z3s Chain D

Receptor sequence
>6z3sD (length=468) Species: 508771 (Toxoplasma gondii ME49) [Search protein sequence]
ADGPYSGILDSVLDAIGNTPMVRMKRLAKVYGLECDLLAKCEFMSAGGSV
KDRIGKAMVEKAEREGRLKAGDTLIEPTSGNTGIGLALAAAVRGYRMIVT
MPAKMSAEKSNIMKCLGAEIVRTPTEAAWNDENSHMGVAAKLQRELENAH
ILDQYNNTANPMVHYDVTAEEIITQCDGDIDMVVIGAGTGGTITGIGRKI
KERCPKCKVVGVDPKGSILAVPDSLNDEKRLQSYEVEGIGYDFVPGVLDR
KVVDEWVKVGDAESFTTARAIIRNEGLFVGGSSGANVWGALQAARQLKKG
QKCVVLLPDSSRNYMSKFISDEWMAEHGFAPEDGAKVKEREKQFGGARIR
DLLSETGTSDVPFVTARLSVEDVIKMMHETKVKEVIVTEDLVGVLSEDHI
AHSLQSGRCAMQSPVKDIAFKKLAKALPSAYLRDVAKALDFSPYVCVMDP
HFLGVITRIDLLHWLATK
3D structure
PDB6z3s Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii .
ChainD
Resolution3.048 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.22: cystathionine beta-synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P1T D K56 T83 S84 N86 T87 Q159 G193 T194 G195 T197 G243 S287 P313 D314 K51 T78 S79 N81 T82 Q154 G188 T189 G190 T192 G238 S282 P308 D309
Gene Ontology
Molecular Function
GO:0004122 cystathionine beta-synthase activity
GO:0016829 lyase activity
Biological Process
GO:0006534 cysteine metabolic process
GO:0006535 cysteine biosynthetic process from serine
GO:0009069 serine family amino acid metabolic process
GO:0019343 cysteine biosynthetic process via cystathionine
GO:0019344 cysteine biosynthetic process
GO:0044272 sulfur compound biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:6z3s, PDBe:6z3s, PDBj:6z3s
PDBsum6z3s
PubMed34194677
UniProtA0A125YSJ9

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